HumanEnos Technology

HumanEnos Technology

World’s First
Patented Natural Fermentation Nitric Oxide

A patented natural fermentation technology developed to safely replenish depleted nitric oxide in the human body.

4th Generation Fermented Nitric Oxide

Unlike traditional nitric oxide supplements, which rely on supplying NO precursors to cells with NOS (nitric oxide synthase) enzymes, HumanNOS technology enables the supply of NO metabolites to all cells in the body.

* Generational Nitric Oxide Delivery Methods and Characteristics

1G

Nitroglycerin

Nitric Oxide Donor

Issues

  • Long-term organ damage
  • Difficulty in precisely delivering nitric oxide to targeted areas
  • Generation of carcinogenic substances (free radicals) during nitric oxide production

2G

Arginine

Nitric Oxide Precursor

Issues

  • Supplies nitric oxide only to cells with NOS enzymes
  • Unable to supply nitric oxide if cells with NOS enzymes are damaged
  • Nitric oxide conversion rate in the body: less than 5%

3G

Chemical Metabolites

Single Nitric Oxide Metabolite

Issues

  • Relies on bacterial enzymes for absorption in the body
  • May react with secondary amines to produce carcinogenic substances (nitrosamines)

Dependent on liver and bacterial enzymes
Potential formation of carcinogenic nitrosamines when combined with secondary amines

4G

Fermented Metabolites

Complex Nitric Oxide Metabolites | HumanNOS Specialized Technology

Issues

  • Does not use bacterial enzymes, enabling maximum absorption in the body
  • Blocks the formation of carcinogenic substances from secondary amines
  • Produces nitric oxide through fermentation of animal, plant, and mineral materials (mimicking the body’s natural production mechanisms, generating bioactive metabolites such as RNO, GSNO, NO2, NO3, GSH, GSSG)
  • Supplies 100% of the body’s deficient nitric oxide and antioxidant nutrients
  • No nitrosamine formation

Enzyme-independent
Produces protective substances that block reactions with secondary amines, preventing carcinogenic substance formation

Why Metabolites Instead of Precursors? Precursors supply nitric oxide only to cells with NOS enzymes, while metabolites can deliver nitric oxide to all cells.

The Gift of Time,
HumanEnos 4th Generation Microbial Fermentation Technology

HumanEnos's fermentation process fully decomposes organic matter over 20 to 90 days, depending on the material, transforming it into metabolites to maximize absorption in the body. The 4th generation microbial fermentation technology, which produces essential substances through sufficient fermentation, is truly a gift of time.

Glutathione Stabilization, a Key Antioxidant in Nitric Oxide and Antioxidant Nutrients

Enhanced nutrient absorption through metabolite conversion, increasing bioavailability

Toxins are broken down and eliminated, while beneficial pharmacological components are increased

Components identical to the body’s nitric oxide are fully excreted, with minimal side effects

Excellence of HumanNOS Technology

Starting with the world’s first patent for a nitric oxide supplementation method in 2020, this technology, driven by an unwavering commitment to human health and happiness, was developed to replenish depleted nitric oxide in the body.

Nitrogen-Containing Natural Substances

Patented Microorganisms

(KCTC12501BP)

Biotransformation Engineering Technology

Natural Nitric Oxide Metabolites

Antioxidant Nutrients

Complex Nitric Oxide Substances

Nitric Oxide Supply in the Body

Nutrient Supply

Role

HumanEnos’s fermentation technology produces metabolites and various functional substances based on the fermented material. The preservative-free natural nitric oxide metabolites offer benefits such as increased absorption, toxin breakdown, enhanced pharmacological components, prevention of color degradation, and odor elimination.
Functionality of Superfood Fermented Products
Reborn with HumanEnos Fermentation Technology

Lettuce

Lactucin

Sleep improvement effects

Garlic

Allicin

Increases body temperature

Enhances immunity

Soybean

Isoflavones

Improves menopausal symptoms

Promotes women’s health

Cabbage

Vitamin U

Supports stomach health

Results of HumanEnos Fermentation Technology

Compared to HumanEnos’s garlic fermentation liquid, Company S’s Product P and Company H’s Product N generated significantly lower amounts of nitric oxide (NO). In comparison to Company N’s Product N, HumanNOS’s product produced approximately 12 times more nitric oxide (NO).

Our Garlic Fermentation Liquid

Neo40(Neogenis)

Products

HumanEnos Product

Company N’s Product N

Company S’s Product P

Company H’s Product N

Nitric Oxide Production (per dose)

276

μmol/per

22.18

μmol/per

0.11

μmol/per

0.15

μmol/per